1950 - 1960: William and Frank Fry treated with HIFU the patients with Parkinson’s disease and other neurological problems.
1989: Dr. Wang Zhibiao and Prof. Ruo Feng began the researches concerning the ultrasounds effects upon the tissues.
1996: Dr. Wang Zhibiao and his collaborators treated for the first time a bone tumor on a patient at the Ultrasounds Medical Engineering Institute of the University of Medical Sciences from Chongqing .
At the moment, the HIFU, discovered and developed by Dr. Wang Zhibiao and Prof. Ruo Feng, is used in more than 300 hospitals in China.
World-wide, the equipment is used in China and in other countries like: England, Italy, Spain, and Russia.
Since 2009, Romania is the fourth country within the European Community where such equipment is operational and where the ablation by ultrasounds conformational hyperthermia is put into practice.